Grading Essays That Compare Henrietta Lacks to the Tuskegee Study

Published on September 24th, 2026 by the GraideMind team

Courses that cover multiple historical instances of medical ethics violations often pair The Immortal Life of Henrietta Lacks with the Tuskegee syphilis study, since both cases involve Black patients whose trust was betrayed by medical institutions, but the two cases differ enough in structure and intent that a lazy comparison essay can flatten important distinctions between them. The Tuskegee study involved active, deliberate withholding of treatment over decades as part of a designed research protocol, while the Lacks case involved a single unconsented tissue extraction followed by decades of institutional silence rather than an ongoing deliberate experiment. Grading comparative essays on these two cases requires a rubric that rewards precision about these differences rather than treating both cases as interchangeable examples of the same general wrongdoing.

A stack of exam papers waiting to be graded

A strong comparative essay identifies at least one meaningful point of similarity and one meaningful point of difference between the two cases, rather than simply cataloging surface level parallels like "both involved Black patients" without deeper analysis of what those parallels reveal about patterns in medical ethics. A useful similarity worth pushing students toward is the shared pattern of institutions prioritizing research value over patient welfare and communication, which appears in different forms in both cases but reflects a common institutional failure mode worth naming explicitly. A useful difference worth pushing students toward is the distinction between active harm through withheld treatment in Tuskegee versus passive harm through disregard and silence in the Lacks case, since conflating these two different mechanisms of harm produces a less precise, less analytically useful essay.

Grading should specifically check whether students maintain this precision throughout the essay rather than letting the two cases blur together after an initial paragraph that distinguishes them. It is common for students to draw a careful distinction early in the essay and then lose that precision in later paragraphs, referring to both cases interchangeably once they move into broader argument about institutional patterns. A rubric note flagging this specific pattern, asking teachers to check paragraph by paragraph whether the case-specific details remain accurate throughout the whole essay rather than only in the introduction, catches a genuine and common weakness in this kind of comparative writing.

Weighting Comparison Quality in the Rubric

Because the entire point of a comparative essay is the quality of the comparison itself, that dimension should carry significant weight in the rubric, arguably more than in a single case analytical essay where the comparison element does not exist. A rubric category specifically labeled "comparative precision" or similar, checking whether the essay identifies genuine points of alignment and divergence with specific evidence from both cases, gives teachers a clear place to evaluate this central skill rather than folding it into a more generic "argument quality" category that might miss whether the comparison itself was actually done well.

  • Require at least one specific point of genuine similarity supported by evidence from both cases
  • Require at least one specific point of genuine difference supported by evidence from both cases
  • Check whether case-specific precision holds throughout the essay, not just in the introduction
  • Score comparative precision as its own rubric category given its centrality to the assignment
  • Flag essays that treat both cases as interchangeable examples without real distinction

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A comparison only teaches something real once it accounts for how the two cases actually differ.

Avoiding a Hierarchy of Suffering

Comparative essays on this topic sometimes drift, usually unintentionally, into ranking which case was "worse," which can feel reductive given the real human suffering involved in both situations and tends to produce shallower analysis than essays that instead focus on what each case reveals about different mechanisms of institutional harm. Teachers should address this directly in the prompt and rubric, explicitly discouraging a simple ranking approach and instead asking students to explain what is distinctly revealing about each case rather than which one deserves more moral condemnation. This framing shift, from ranking to distinct revelation, tends to produce more sophisticated student writing and also avoids the pedagogically uncomfortable position of grading students on whether they ranked historical suffering correctly.

When students do drift toward a ranking framework despite this guidance, feedback should redirect them toward the more productive comparative question rather than simply marking the ranking approach as wrong without explanation. A comment like "instead of deciding which case was worse, try explaining what each case teaches us about a different way institutions fail patients" gives students a concrete alternative framework to work with rather than leaving them unsure how to revise an essay that has been flagged as taking the wrong approach.

Extending the Comparison to a Third, Student-Chosen Case

For more advanced courses, extending the comparison to include a third case the student researches independently, chosen from a list of other documented medical ethics violations, pushes the assignment further and tests whether students can apply the comparative framework they practiced on Lacks and Tuskegee to a new, less familiar case. This extension raises the difficulty and the grading complexity somewhat, since teachers now need some familiarity with whatever third case each student selects, but it also produces genuinely more sophisticated final essays from students who are ready for the additional challenge.

Grading this extended version requires trusting students' research and giving them the benefit of the doubt on factual details from the third case that the teacher may not know as thoroughly as the two primary cases covered in class, while still holding them to the same standard of comparative precision established earlier in the unit. A brief citation requirement for the third case, at minimum a credible source establishing the key facts being compared, gives teachers a way to verify accuracy without needing deep independent expertise in every possible case a student might choose to research and include in their extended comparison.

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